This video explains how CBD oil is different from THC & benefits
WILD12 Channel, we share information of CBD
此外，CBD激活5-HT1A / 2A / 3A 5-羥色胺(血清素)受體。
There has recently been a huge interest in CBD oil for its many therapeutic benefits. In this video
oil actually works. There are at least 85 active cannabinoids in cannabis. Of these 85 cannabinoids the two main neuroactive ones are psychoactive tetrahydrocannabinol or THC for short and non -psychoactive cannabidiol or CBD for short. Cannabidiol is the component that makes up
CBD oil. So how does THC and CBD work and why does THC have psychoactive effects and CBD doesn’t. Well in the body system. This consists of two G-protein-coupled receptors called cannabinoid type 1 receptors and cannabinoid type 2 receptors. CB1 receptors are found in the central and peripheral nervous system with most of them being in the hippocampus and amygdala in the brain. So CB1 receptors are primarily found in the brain and mainly effect mood. CB2 receptors are found in our immune cells lymphoid tissue and peripheral nerve terminals. So CB2 receptors are primarily found in the body and mainly effect the immune system and inflammation.
THC is a weak partial agonist of CB1 and CB2 receptors. Which basically means it activates and stimulates the receptors. Now as mentioned found in the brain and amygdala. The hippocampus and amygdala are involved in the regulation of memory and by THC activating these receptors
leads to the popular effects of an increased appetite and cognitive processes. This is how THC has psychoactive properties. Now CBD also has a link with CB1 and CB2 receptors but in a different way to THC. As we covered and so directly stimulates the receptors. CBD however is an allosteric modulator. This means that it doesn’t directly attach to the cannabinoid receptors to activate them but instead, it increases how receptive the receptors are to the natural endocannabinoids
in our body. Endocannabinoids are made in our body and we also get them from our diet. So CBD basically enhances the receptor action in a natural way rather than directly activating it. This indirect approach means that we don’t get the same psychoactive effects as THC. And so the anti-pain and anti-anxiety effects that comes from CBD oil may be influenced by enhancing the action of CB1 receptors. And the anti-inflammatory and anti-oxidant effects that come from CBD oil may be influenced by enhancing the action of CB2 receptors. Moreover receptors. Serotonin is the feel good chemical in our body and the activation of the specific 5-HT1A and 2A receptors may be responsible for anti-depressant and anti-anxiety properties. TRPV1-2 vanillin receptors are also activated by CBD and these receptors are responsible for the regulation of body temperature and inflammation. CBD is also known to: deactivate alpha-1 adrenergic and opioid receptors uptake of noradrenaline and GABA thus prolonging their effect on mitochondria calcium stores activated T-type calcium channels
the activity of the inhibitory glycine-receptor and inhibit the activity of fatty amide hydrolase. Basically, areas in the body and this could be the reason why it’s also known to have anticonvulsant
muscle relaxant anti-oxidant and antiemetic effects. However in the early stages of research.
Its interaction with other medication side effects and how safe it is in the long term are still not fully known. Therefore stores to buy this oil and instead to refer to a doctor who can give more personalized and educated advice on whether CBD oil is suitable for you or not. If you have found this video interesting please subscribe to the channel and check out the other videos.